“We do not develop protective immunity against omicron”: New study suggests that those who have omicron are not immune to re-infection

“We do not develop protective immunity against omicron”: New study suggests that those who have omicron are not immune to re-infection

Contracting the Omicron variant does not increase the immunity of carriers and does not reduce their risk of re-infection, according to a new study conducted in the UK. The statement applies to anyone who has received all three doses of the vaccine. According to the study, the first wave of epidemic does not show any improvement in the immune system of people infected with Kovid, if they eventually succumb to the Omicron type.

The study was published on Tuesday Science Omicron can help explain why there are so many cases of re-infection in the wave, including cases of people who have had Omicron twice collapsed, as well as the need for herd immunity.

New research suggests that new compresses may be a way to gain immunity against the virus, or to prevent re-infection. “When Omicron started flying across the country, people said everything was fine, it was a way to improve people’s immunity,” said Rosemary Boyton, co-author of the study at Imperial College London, in a statement from her university. , Concludes: “What we are saying is that it is not a good immunity booster”.

For those who were triple-vaccinated and did not have a previous covid infection, omikron developed a more pronounced resistance to earlier types and much smaller against omikron. Those who were re-infected with Omicron during and after the first wave of epidemic disease did not have any kind of reinforcement. “If you get infected during the first wave, you can’t boost your immune system if you have an Omicron infection,” says Boyton.

Nevertheless, and although vaccines do not prevent re-infection, the study team warns that vaccination is necessary to protect against the more serious consequences of covid infection.

The study was based on a sample of 731 UK healthcare workers, all of whom were triple vaccinated but had a different history of infection, which was followed between March 2020 and January 2022. Samples collected the following week were used by the team. The third dose sought to detect the responses of antibodies and subvariant BA.1, the Omicron type of two cell types known as T and B cells.

The results suggested that, regardless of whether participants were already infected with covid, in the week after the third dose, their T cell levels decreased against omikron proteins, while their antibody levels against omikron proteins decreased significantly. Against other variants.

However, a few other findings drawn during the study have shown that the history of infection is important. According to the research team, infection with the Omicron variant increases protection against future infections with other types, but it does not do so, or at least not significantly, against Omicron reinfection. If they are infected with the first wave of the virus and then with Omicron, their immunity becomes even weaker.

“Immune Imprint”

The discovery dispelled the notion that any type of infection is a way to boost a person’s immune system. Conversely, it seems that a person’s protection from future infections varies according to the history of any type of infection and the history of vaccination, known as “immune imprinting”.

According to the researchers, this diversity in the history of infection and vaccination was essential to study participants because it enabled them to better understand not only the virus but also the importance of the immune system. Future new variants or swarm immunity.

The findings suggest that those who have never been infected with Covid-19 and who became infected with Omicron only after receiving three doses of the vaccine had better immunity to B and T cells in laboratory tests against earlier forms such as alpha and delta, although with less protection. Omicron v. At the onset of the epidemic, those with alpha infection had a lower antibody response to omicron.

Studies have shown that Omicron has a debilitating effect on the immune system of individuals. “We found that the Omicron vaccine is far from a mild natural booster of immunity, as we might have thought, but it is particularly a latent immune defender,” study co-author Danny Altman explained in a statement.

According to Altman, new discoveries may be important, even in the development of new vaccines that may be needed, especially now that the myth of herd immunity has been dispelled. “We are not getting herd immunity, we are not building protective immunity for Omicron,” he said.

Yet, in many parts of the world, the new wave of covid seems to be more or less the cause of hospitalization and other serious consequences. This suggests that, despite the fact that people have a history of infection or vaccination, they appear to be developing immunity against the most severe forms of covid. However, it is important to note that Omicron’s immune system and new subtypes are evolving, the study authors noted.

“One concern is that Omicron may mutate,” Boyton explains. “In this case, people who have been infected with Omicron, depending on their ‘immune imprinting’, will be significantly stronger against future infections,” he added.

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