US approves drug to treat severe alopecia

US approves drug to treat severe alopecia

The US Food and Drug Administration (FDA) this week authorized a drug against a severe form of alopecia, a disease that causes hair loss and affects more than 300,000 people a year in the United States alone. Baricitinib, manufactured by pharmacist Eli Lilly and sold under the name Oluminant, belongs to the class of anti-inflammatory drugs and is the first oral pill to treat alopecia areata.

O Baricitinib Treatment for rheumatoid arthritis had already been authorized and permission was extended to patients with severe forms of Covid-19.

The following is an FDA drug authorization for the treatment of the following acute forms: Two clinical trials involving a total of 1,200 adults with alopecia areataA disease where the immune system attacks the hair follicles and causes hair or fur to fall off temporarily or permanently in certain parts of the body.

For each clinical trial, Participants were divided into three groups: One-third received placebo, another third received 2 mg daily dose, and third received 4 mg daily dose. After 36 weeks, the results were:

  • Nearly 40% of patients who took the highest dose had 80% hair growth, compared to about 23% who took the low dose and 5% who took placebo.
  • About 45% of people who received 4 mg had significant hair growth in some areas, especially on the eyebrows.

The most common side effects reported during clinical trials are upper respiratory tract infections, headaches, acne, high cholesterol and increased presence of an enzyme called creatinine kinase.

Other treatments have been tried to treat alopecia areata, but none have been approved by the FDA.

“Significant access to safe and effective treatment options is critical for a significant number of Americans with severe alopecia.”An FDA official said. Kendall Marcus concluded, “This move will help meet the critical needs of patients with the disease.

Alopecia is a disease that occurs when the immune system attacks the hair follicles, hair loss or hair loss can be temporary or even permanent, which can cause a lot of emotional distress.

Recently, the disease has become more popular, when public statistics such as Actress Jada Pinkett Smith or Democrat Aina Presley It was revealed that they had.

Will Smith and Jada Pinkett Smith at the Oscars, March 27, 2022. (AP)

Will Smith’s aggression against Chris Rock at the Oscars ceremony also indirectly contributed to the publicity of this health problem. Rock joked about the extra, Will Smith’s wife, the actor didn’t like it, went on stage and slapped the comedian.

In general, alopecia can affect both sexes, but it is more common in men. The disease usually manifests before the age of 30, but can occur at any time in life with young children and young people.

There are several types of alopecia, but the two most common are:

  • Alopecia areata – Hair or hair loss can occur anywhere on the body such as scalp, beard, armpits etc.
  • Androgenetic alopecia – Related to hormonal or genetic problems, mainly affects men and is related to baldness.

Other types of alopecia are also identified, though less frequently:

  • Extremely painful alopecia – It is related to a head injury or is caused by mechanical traction of the hair, i.e. specific hair follicles that can cause hair loss.
  • seborrheic alopecia – Seborrheic dermatitis, inflammation that affects the scalp and causes oiliness, dandruff and itching.

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